| The Irish Descendants | Folk |
| Indila | Pop |
| Iron Maiden | Rock |
| Inner Circle | Electronic |
| Incubus | Rock |
| Imago | Rock |
| Israel | |
| Inna | Electronic |
| Israel Kamakawiwo'ole | Folk |
| Itchyworms | Rock |
| Imitator Tots | Other |
| IV Of Spades | Other |
| Iris Dement | Country |
| Ikimono Gakari | Rock |
| Irving Berlin | Jazz |
| Inxs | Rock |
| The Isley Brothers | R&B |
| Il Divo | Pop |
| Iñigo Pascual | Other |
| Iggy Azalea | Pop |
| Insane Clown Posse | Hip-Hop |
| Ice Cube | Hip-Hop |
| Iggy Pop | Rock |
| Ima Robot | Rock |
| In This Moment | Metal |
| India Arie | |
| Iyeoka | Pop |
| Ina-P | Other |
| Il Volo | Rock |
| Ian Dury & The Blockheads | Rock |
| Insomnium | Metal |
| Immortal | Metal |
| Indigo Girls | Rock |
| Imogen Heap | Electronic |
| Iyaz | Pop |
| Interpol | Rock |
| Isaac Hayes | R&B |
| The Inspirations | Other |
| Isaacs | |
| Indecent Obsession | Pop |